Tryptanthrin 是一种口服具有活性的细胞内Leukotriene (LT) biosynthesis抑制剂。 它能够降低大鼠胸膜炎模型中的 LTB4 水平，并抑制人全血中Leukotriene 的形成 (IC50= 10 μM)。

Tryptanthrin is a natural DNA gyrase inhibitor.

Tryptanthrin?blocks signaling through VEGFR2 at the level of ERK1/2 signaling in vitro[1]

Tryptanthrin suppresses angiogenesis in vivo[1]

13220-57-0

C15H8N2O2

248.24

DMSO:8 mg/mL (32.22 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years