Metformin D6 hydrochloride

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本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

1185166-01-1

包装与价格：

包装	价格(元)
1mg	电议
5mg	电议

产品介绍

MetforminD6hydrochloride是Metforminhydrochloride的一种氘代化合物。Metforminhydrochloride抑制肝脏中的线粒体呼吸链，导致AMPK活化，增强胰岛素敏感性，可用于2型糖尿病的研究。Metforminhydrochloride可以透过血脑屏障，诱导自噬(autophagy)。

Cas No.	1185166-01-1
别名	二甲双胍盐酸,1,1-Dimethylbiguanide-d6 hydrochloride
Canonical SMILES	NC(NC(N(C([2H])([2H])[2H])C([2H])([2H])[2H])=N)=N.[H]Cl
分子式	C₄H₆D₆ClN₅
分子量	171.66
储存条件	Store at -20℃
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
产品描述	Metformin D6 hydrochloride is a deuterium labeled Metformin hydrochloride. Metformin hydrochloride inhibits the mitochondrial respiratory chain in the liver, leading to activation of AMPK, enhancing insulin sensitivity for type 2 diabetes research. Metformin hydrochloride triggers autophagy[1]. [1]. Soraya H, et al. Acute treatment with metformin improves cardiac function following NSC 37745 induced myocardial infarction in rats. Pharmacol Rep. 2012;64(6):1476-84.