产品介绍 目录号
Serial | TCHu 23 | 标识符
Identifier | CSTR:19375.09.3101HUMTCHu23 | 描述
Description | HL-60是一株早幼粒细胞。 外周血白细胞来自一位患有急性粒-单核细胞白血病的36岁白人女性。 HL-60 自发分化，丁酸盐、次黄嘌呤、佛波醇肉豆蔻酸(PMA,TPA)、DMSO(1% to 1.5%)、放线菌素D和视黄酸可以促进分化。 细胞表现出吞噬活性，并对趋化刺激有响应。致癌基因myc表达阳性。
在本库通过支原体检测。
在本库通过STR检测。 | 动物种别
Organism | 人 | 性别
Gender | 女 | 组织来源
Tissue and Cell Type | 外周血；早幼粒细胞；急性粒－单核细胞白血病 | 形态
Morphology | 原粒细胞 | 培养基和添加剂
Complete Growth Medium and Culture Conditions | IMDM培养基(GIBCO,货号12200036)，80%；优质胎牛血清，20%。
气相：空气，95%；二氧化碳，5%。
温度：37摄氏度。 | 供应限制
Permits and Restrictions | A。仅供研究之用。 | | REFERENCE | Gallagher R , et al. Characterization of the continuous, differentiating myeloid cell line (HL-60) from a patient with acute promyelocytic leukemia. Blood 54: 713-733, 1979. PubMed: 288488Collins SJ , et al. Terminal differentiation of human promyelocytic leukemia cells induced by dimethyl sulfoxide and other polar compounds. Proc. Natl. Acad. Sci. USA 75: 2458-2462, 1978. PubMed: 276884Collins SJ , et al. Continuous growth and differentiation of human myeloid leukaemic cells in suspension culture. Nature 270: 347-349, 1977. PubMed: 271272Aggarwal BB , et al. Human tumor necrosis factor. Production, purification, and characterization. J. Biol. Chem. 260: 2345-2354, 1985. PubMed: 3871770Nahm MH , et al. Identification of cross-reactive antibodies with low opsonophogocytic activity for Streptoccus pneumoniae. J. Infect. Dis. 176: 698-703, 1997. PubMed: 9291318Berninghausen O , Leippe M . Necrosis versus apoptosis as the mechanism of target cell death induced by Entamoeba histolytica. Infect. Immun. 65: 3615-3621, 1997. PubMed: 9284127Aparicio CL , et al. Correction for label leakage in fluorimetric assays of cell adhesion. BioTechniques 23: 1056-1060, 1997. PubMed: 9421636Mansat V , et al. The protein kinase C activators phorbol esters and phosphatidylserine inhibit neutral aphingomyelinase activation, ceramide generation, and apoptosis triggered by daunorubicin. Cancer Res. 57: 5300-5304, 1997. PubMed: 9393753Cuthbert JA , Lipsky PE . Regulation of proliferation and Ras localization in transformed cells by products of mevalonate metabolism. Cancer Res. 57: 3498-3504, 1997. PubMed: 9270019Michael JM , et al. Resistance to radiation-induced apoptosis in Burkitt's lumphoma cells is associated with defective ceramide signaling. Cancer Res. 57: 3600-3605, 1997. PubMed: 9270034Clark RA , et al. Tenascin supports lymphocyte rolling. J. Cell Biol. 137: 755-765, 1997. PubMed: 9151679Tiffany HL , et al. Enhanced expression of the eosinophil-derived neurotoin ribonuclease (RNS2) gene requires interaction between the promoter and intron. J. Biol. Chem. 271: 12387-12393, 1996. PubMed: 8647842Chan YJ , et al. Synergistic interactions between overlapping binding sites for the serum response factor and ELK-1 proteins mediate both basal enhancement and phorbol ester responsiveness of primate cytomegalovirus. J. Virol. 70: 8590-8605, 1996. PubMed: 8970984Mao M , et al. RIG-E, a human homolog of the murine Ly-6 family, is induced by retinoic acid during the differentiation of acute promyelocytic leukemia cell. Proc. Natl. Acad. Sci. USA 93: 5910-5914, 1996. PubMed: 8650192Lepley RA , et al. Tyrosine kinase activity modulates catalysis and translocation of cellular 5-lipoxygenase. J. Biol. Chem. 271: 6179-6184, 1996. PubMed: 8626407Chen H , et al. Octamer binding factors and their coactivator can activate the murine PU.1 (spi-1) promoter. J. Biol. Chem. 271: 15743-15752, 1996. PubMed: 8663022Chinese Tumor 11(5):305-306,2002China J Cancer Prev Treat 9(1):11-14,2002Chin J Hematol 23(4):176-178,2002Jiangsu Med J. 28(10):735-737,2002Chin J Hematol 24(5):231-234,2003Chin J Hematol 24(12):640-643,2003China Oncology 13(2):125-127,2003Journal of Xiamen University (Natural Science) 42(4):513-516,2003Immunological Journal 19(1):26-29,2003Immunological Journal 19(3):198-200,2003Acta Academae Medicinae Miltaris Tertiae 25(24):2212-2215,2003 |
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