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APXL蛋白抗体
产品介绍 靶标: SHROOM2 产品别名: APXL; HSAPXL; SHROOM2; shroom family member 2; shroom family member 2; protein Shroom2; APX homolog of Xenopus; apical-like protein; APXL蛋白; 背景信息: Shroom family member 2 is a protein that in humans is encoded by the SHROOM2 gene. This gene represents the human homolog of Xenopus laevis apical protein (APX) gene, which is implicated in amiloride-sensitive sodium channel activity. It is expressed in endothelial cells and facilitates the formation of a contractile network within endothelial cells. Depletion of this gene results in an increase in endothelial sprouting, migration, and angiogenesis. This gene is highly expressed in the retina, and is a strong candidate for ocular albinism type 1 syndrome. Alternatively spliced transcript variants have been found for this gene. 宿主:Rbt |
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