产品介绍 靶标： PTPRG 产品别名： HPTPG； PTPG； R-PTP-GAMMA； RPTPG； PTPRG； protein tyrosine phosphatase receptor type G； protein tyrosine phosphatase receptor type G； receptor-type tyrosine-protein phosphatase gamma； H_RG317H01.1； protein tyrosine phosphatase gamma； protein tyrosine phosphatase, receptor type, gamma polypeptide； receptor type protein tyrosine phosphatase gamma； receptor tyrosine phosphatase gamma； receptor-type protein phosphatase gamma； 蛋白酪氨酸磷酸酶受体G(PTPRG)； 背景信息： The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. This gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene. [provided by RefSeq, Jul 2008], 宿主：Rbt |
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