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胸苷激酶2抗体
产品介绍 靶标: TK2 产品别名: MTDPS2; MTTK; PEOB3; SCA31; TK2-EXT; TK2; thymidine kinase 2; thymidine kinase 2; thymidine kinase 2, mitochondrial; thymidine kinase 2; 2'-deoxyuridine kinase TK2; deoxycytidine kinase TK2; mitochondrial thymidine kinase; mt-TK; 胸苷激酶2; 背景信息: Thymidine kinase 2, mitochondrial is a protein that in humans is encoded by the TK2 gene. This gene encodes a deoxyribonucleoside kinase that specifically phosphorylates thymidine, deoxycytidine, and deoxyuridine. The encoded enzyme localizes to the mitochondria and is required for mitochondrial DNA synthesis. Mutations in this gene are associated with a myopathic form of mitochondrial DNA depletion syndrome. Alternate splicing results in multiple transcript variants encoding distinct isoforms, some of which lack transit peptide, so are not localized to mitochondria. 宿主:Rbt |
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