产品介绍 靶标: USP6 产品别名: HRP1; TRE17; TRE2; TRESMCR; Tre-2; USP6-short; USP6; ubiquitin specific peptidase 6; ubiquitin specific peptidase 6; ubiquitin carboxyl-terminal hydrolase 6; TBC1D3 and USP32 fusion; deubiquitinating enzyme 6; hyperpolymorphic gene 1; proto-oncogene TRE-2; ubiquitin specific peptidase 6 (Tre-2 oncogene); ubiquitin specific protease 6 (Tre-2 oncogene); ubiquitin thioesterase 6; ubiquitin thiolesterase 6; ubiquitin-specific protease USP6; ubiquitin-specific-processing protease 6; 背景信息: catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,disease:Involved in tumorigenesis.,function:Has an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity.,miscellaneous:The USP6 gene only exists in the primate lineage.,similarity:Belongs to the peptidase C19 family.,similarity:Contains 1 Rab-GAP TBC domain.,tissue specificity:Testis specific. Expressed in various cancer cell lines., 宿主:Rbt |
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