产品介绍 靶标: ARHGAP32 产品别名: GC-GAP; GRIT; PX-RICS; RICS; p200RhoGAP; p250GAP; ARHGAP32; Rho GTPase activating protein 32; Rho GTPase activating protein 32; rho GTPase-activating protein 32; GAB-associated CDC42; GAB-associated Cdc42/Rac GTPase-activating protein; GTPase regulator interacting with TrkA; GTPase-activating protein for Cdc42 and Rac1; RhoGAP involved in the -catenin-N-cadherin and NMDA receptor signaling; brain-specific Rho GTP-ase-activating protein; brain-specific Rho GTPase-activating protein; rac GTPase activating protein; rho-type GTPase-activating protein 32; rho/Cdc42/Rac GTPase-activating protein RICS; rhoGAP involved in the beta-catenin-N-cadherin and NMDA receptor signaling; Rho GTP酶激活蛋白32; 锚蛋白重复结构域蛋白17; 背景信息: GTPase-activating protein (GAP) promoting GTP hydrolysis on RHOA, CDC42 and RAC1 small GTPases. May be involved in the differentiation of neuronal cells during the formation of neurite extensions. Involved in NMDA receptor activity-dependent actin reorganization in dendritic spines. May mediate cross-talks between Ras- and Rho-regulated signaling pathways in cell growth regulation. Isoform 2 has higher GAP activity (By similarity). 宿主:Rbt |
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