产品介绍 靶标: FARP1 产品别名: CDEP; FARP1-IT1; GLCC1; PLEKHC2; PPP1R75; FARP1; FERM, ARH/RhoGEF and pleckstrin domain protein 1; FERM, ARH/RhoGEF and pleckstrin domain protein 1; FERM, ARHGEF and pleckstrin domain-containing protein 1; FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived); FERM, RhoGEF and pleckstrin domain-containing protein 1; PH domain-containing family C member 2; chondrocyte-derived ezrin-like protein; glycolysis-associated lncRNA of colorectal cancer; pleckstrin homology domain-containing family C member 2; protein phosphatase 1, regulatory subunit 75; 软骨细胞Ezrin样蛋白; 背景信息: Aminoacyl-tRNA synthetases consist of a family of enzymes that catalyze the specific aminoacylation of tRNA by their cognate amino acid in the initial step of ribosome-dependent protein biosynthesis. FARSLA, also known as FRSA, CML33, FARSL or PheHA (phenylalanyl-tRNA synthetase, alpha subunit), is a member of the class-II aminoacyl-tRNA synthetase family and is highly expressed in proliferating cells of bone marrow. FARSLA is a cytoplasmic phenylalanine-tRNA synthetase that functions as a heterodimer consisting of a catalytic alpha-subunit and a regulatory beta-subunit. The alpha-subunit is responsible for forming the amino acid binding pocket, mediating the ATP aminoacyl adenylate binding, and interacts with the acceptor stem of the tRNA. FARSLA functions in a cell cycle-dependent and differentiation-dependent manner. 宿主:Rbt |
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