产品介绍 靶标: TCIRG1 产品别名: ATP6N1C; ATP6V0A3; Atp6i; OC-116kDa; OC116; OPTB1; Stv1; TIRC7; Vph1; a3; TCIRG1; T cell immune regulator 1, ATPase H+ transporting V0 subunit a3; T cell immune regulator 1, ATPase H+ transporting V0 subunit a3; V-type proton ATPase 116 kDa subunit a 3; ATPase, H+ transporting, 116kD; T-cell immune response cDNA 7; T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein a; T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3; V-ATPase 116 kDa subunit a 3; V-ATPase 116 kDa subunit a3; V-ATPase 116-kDa; V-ATPase subunit a3; V-type proton ATPase 116 kDa subunit a; V-type proton ATPase 116 kDa subunit a3; osteoclastic proton pump 116 kDa subunit; specific 116-kDa vacuolar proton pump subunit; vacuolar proton translocating ATPase 116 kDa subunit A; T-细胞免疫调节因子1(TCIRG1); 背景信息: This gene encodes a subunit of a large protein complex known as a vacuolar H+-ATPase (V-ATPase). The protein complex acts as a pump to move protons across the membrane. This movement of protons helps regulate the pH of cells and their surrounding environment. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. V-ATPase is comprised of a cytosolic V1 domain and a transmembrane V0 domain. Alternative splicing results in multiple transcript variants. Mutations in this gene are associated with infantile malignant osteopetrosis. 宿主:Rbt |
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