产品介绍 靶标: Asap1 产品别名: AV239055; DEF-1; Ddef1; PAP; mKIAA1249; s19; Asap1; ArfGAP with SH3 domain, ankyrin repeat and PH domain1; ArfGAP with SH3 domain, ankyrin repeat and PH domain1; arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1; 130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase-activating protein; 130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein; ADP-ribosylation factor-directed GTPase-activating protein 1; ARF GTPase-activating protein 1; PIP2-dependent ARF1 GAP; development and differentiation-enhancing factor 1; 发育分化增强因子1; 背景信息: Possesses phosphatidylinositol 4,5-bisphosphate-dependent GTPase-activating protein activity for ARF1 (ADP ribosylation factor 1) and ARF5 and a lesser activity towards ARF6. May coordinate membrane trafficking with cell growth or actin cytoskeleton remodeling by binding to both SRC and PIP2. May function as a signal transduction protein involved in the differentiation of fibroblasts into adipocytes and possibly other cell types (By similarity). Plays a role in ciliogenesis. 宿主:Rbt |
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