产品介绍 靶标: NCKIPSD 产品别名: AF3P21; DIP; DIP1; ORF1; SPIN90; VIP54; WASLBP; WISH; NCKIPSD; NCK interacting protein with SH3 domain; NCK interacting protein with SH3 domain; NCK-interacting protein with SH3 domain; 54 kDa VacA-interacting protein; 54 kDa vimentin-interacting protein; 90 kDa SH3 protein interacting with Nck; SH3 adapter protein SPIN90; SH3 protein interacting with Nck, 90 kDa; WASP-interacting SH3-domain protein; dia interacting protein; dia-interacting protein 1; diaphanous protein interacting protein; wiskott-Aldrich syndrome protein-interacting protein; 波形蛋白相互作用蛋白; 背景信息: NCKIPSD(具有 SH3 结构域的 NCK 相互作用蛋白)(也称为 SPIN90)是一种细胞骨架接头蛋白,参与肌动蛋白细胞骨架的组织和基于肌动蛋白的细胞运动 (1)。乳腺癌基质中 NCKIPSD 表达下调与存活率降低相关。NCKIPSD 调节癌症相关成纤维细胞 (CAF) 中的微管乙酰化 (2)。NCKIPSD 还在调节中枢神经系统的信号转导中发挥作用 (3)。 宿主:Rbt |
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