抗体 >> 其他抗体
富含亮氨酸重复序列蛋白1抗体
产品介绍 靶标: LRRC1 产品别名: LANO; dJ523E19.1; LRRC1; leucine rich repeat containing 1; leucine rich repeat containing 1; leucine-rich repeat-containing protein 1; LANO adapter protein; LAP (leucine-rich repeats and PDZ) and no PDZ protein; LAP and no PDZ protein; 富含亮氨酸重复序列蛋白1; 背景信息: Lano is a member of the LAP (leucine-rich repeats and PDZ) family of proteins that also includes Densin-180, Erbin, and hScribble. The LAP proteins generally contain multiple leucine-rich repeat (LRR) domains which serve to target them to the basolateral membrane of epithelial cells. Lano is unique in that it alone does not possess one or more PDZ (PSD95/DLG/ZO-1) domains as do the other members of the LAP family. However, it can bind to the PDZ domain of Erbin in addition to those of membrane-associated and guanylate kinase (MAGUK) proteins which regulate adhesion and plasticity at cell junctions. It has been suggested that it is through these interaction that these LAP proteins participate in the maintenance of proper embryonic development and integrity of epithelial tissues. 宿主:Rbt |
相关产品
|