产品介绍 靶标: CARMIL1 产品别名: CARMIL; CARMIL1a; LRRC16; LRRC16A; dJ501N12.1; dJ501N12.5; CARMIL1; capping protein regulator and myosin 1 linker 1; capping protein regulator and myosin 1 linker 1; F-actin-uncapping protein LRRC16A; CARMIL homolog; capping protein regulator and myosin 1 linker protein 1; capping protein, Arp2/3 and myosin-I linker homolog 1; capping protein, Arp2/3 and myosin-I linker protein 1; capping protein, Arp2/3, and Myosin-I Linker homolog 1; leucine rich repeat containing 16; leucine rich repeat containing 16A; leucine-rich repeat-containing protein 16A; testicular tissue protein Li 107; 背景信息: Cell membrane-cytoskeleton-associated protein that plays a role in the regulation of actin polymerization at the barbed end of actin filaments. Prevents F-actin heterodimeric capping protein (CP) activity at the leading edges of migrating cells, and hence generates uncapped barbed ends and enhances actin polymerization, however, seems unable to nucleate filaments (PubMed:16054028). Plays a role in lamellipodial protrusion formations and cell migration (PubMed:19846667). 宿主:Rbt |
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