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Cited4抗体
产品介绍 靶标: Cited4 产品别名: MRG-2; Mrg2; Cited4; Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4; Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4; cbp/p300-interacting transactivator 4; msg1-related protein 2; 背景信息: Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4(CITED4) Homo sapiens The protein encoded by this intronless gene belongs to the CITED family of transcriptional coactivators that bind to several proteins, including CREB-binding protein (CBP) and p300, via a conserved 32 aa C-terminal motif, and regulate gene transcription. This protein also interacts with transcription factor AP2 (TFAP2), and thus may function as a co-activator for TFAP2. Hypermethylation and transcriptional downregulation of this gene has been observed in oligodendroglial tumors with deletions of chromosomal arms 1p and 19q, and associated with longer recurrence-free and overall survival of patients with oligodendroglial tumors. [provided by RefSeq, Aug 2011], 宿主:Rbt |
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