抗体 >> 其他抗体
MSL1蛋白抗体
产品介绍 靶标: Msl1 产品别名: 2810017F12Rik; 4121402D02Rik; 4930463F05Rik; AA682082; Msl-1; Msl1; male specific lethal 1; male specific lethal 1; male-specific lethal 1 homolog; MSL1-like 1; hampin; male-specific lethal 1-like 1; male-specific lethal-1 homolog 1; MSL1蛋白; 背景信息: Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at 'Lys-16' (H4K16ac which is implicated in the formation of higher-order chromatin structure. Greatly enhances MSL2 E3 ubiquitin ligase activity, promoting monoubiquitination of histone H2B at 'Lys-34' (H2BK34Ub. This modification in turn stimulates histone H3 methylation at 'Lys-4' (H3K4me and 'Lys-79' (H3K79me and leads to gene activation, including that of HOXA9 and MEIS1. In the MSL complex, acts as a scaffold to tether MSL3 and KAT8 together for enzymatic activity regulation. 宿主:Rbt |
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