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甲状腺受体相互作用蛋白8抗体
产品介绍 靶标: Jmjd1c 产品别名: 5430433L24Rik; D630035I23Rik; Jmjdic; TRIP8; Jmjd1c; jumonji domain containing 1C; jumonji domain containing 1C; probable JmjC domain-containing histone demethylation protein 2C; jumonji domain-containing protein 1C; 甲状腺受体相互作用蛋白8; 背景信息: The protein encoded by this gene interacts with thyroid hormone receptors and contains a jumonji domain. It is a candidate histone demethylase and is thought to be a coactivator for key transcription factors. It plays a role in the DNA-damage response pathway by demethylating the mediator of DNA damage checkpoint 1 (MDC1) protein, and is required for the survival of acute myeloid leukemia. Mutations in this gene are associated with Rett syndrome and intellectual disability. Alternative splicing results in multiple transcript variants. 宿主:Rbt |
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