FGD4蛋白抗体

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FGD4蛋白抗体


交货期:	1周
产品别名:	Anti-FGD4 Anti-FYVE, RhoGEF and PH domain containing 4 Antibody

产品介绍

靶标：

FGD4

产品别名：

CMT4H； FRABP； ZFYVE6； FGD4； FYVE, RhoGEF and PH domain containing 4； FYVE, RhoGEF and PH domain containing 4； FYVE, RhoGEF and PH domain-containing protein 4； FGD1 family, member 4； FGD1-related F-actin-binding protein； actin-filament binding protein frabin； zinc finger FYVE domain-containing protein 6； FGD4蛋白；

背景信息：

This gene encodes a protein that is involved in the regulation of the actin cytoskeleton and cell shape. This protein contains an actin filament-binding domain, which together with its Dbl homology domain and one of its pleckstrin homology domains, can form microspikes. This protein can activate MAPK8 independently of the actin filament-binding domain, and it is also involved in the activation of CDC42 via the exchange of bound GDP for free GTP. The activation of CDC42 also enables this protein to play a role in mediating the cellular invasion of Cryptosporidium parvum, an intracellular parasite that infects the gastrointestinal tract. Mutations in this gene can cause Charcot-Marie-Tooth disease type 4H (CMT4H), a disorder of the peripheral nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015],

宿主：Rbt
类型：Pab
同种型:IgG
应用：WB
纯化方式：亲和纯化
偶联物：Unconjugated
性状：液体
存储溶液：参阅说明书
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存：经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。