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FRMPD2抗体
产品介绍 靶标: FRMPD2 产品别名: PDZD5C; PDZK4; PDZK5C; FRMPD2; FERM and PDZ domain containing 2; FERM and PDZ domain containing 2; FERM and PDZ domain-containing protein 2; PDZ domain containing 5C; PDZ domain-containing protein 4; 背景信息: This gene encodes a peripheral membrane protein and is located in a region of chromosome 10q that contains a segmental duplication. This copy of the gene is full-length and is in the telomeric duplicated region. Two other more centromerically proximal copies of the gene are partial and may represent pseudogenes. This full-length gene appears to function in the establishment and maintenance of cell polarization. The protein is recruited to cell-cell junctions in an E-cadherin-dependent manner, and is selectively localized at the basolateral membrane in polarized epithelial cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2009], 宿主:Rbt |
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