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富含半胱氨酸BMP调节蛋白2抗体
产品介绍 靶标: Kcp 产品别名: Crim2; RGD1561119; Kcp; kielin cysteine rich BMP regulator; kielin cysteine rich BMP regulator; kielin cysteine rich BMP regulator; kielin/chordin-like protein; cysteine rich BMP regulator 2 (chordin like); involucrin-like; 富含半胱氨酸BMP调节蛋白2; 背景信息: CRIM2 Antibody: CRIM2, also known as Kielin/chordin-like protein (KCP), is a novel enhancer of BMP signaling. It binds to BMP7, a morphogen that is important for kidney development and part of the kidney's physiological response to repair of acute kidney injury, enhancing its binding to its receptor. Because of this, CRIM2 has been suggested as a potential antifibrotic therapy in acute and chronic kidney injury. CRIM2 can also interact directly with either activin or TGF-β1, suppressing activin- and TGF-β1-dependent transcription. 宿主:Rbt |
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