蛋白质/抗原/多肽 >> 重组蛋白
重组锌指蛋白855
产品介绍 基因名: ZBTB48 产品别名: HKR3; TZAP; ZNF855; pp9964; ZBTB48; zinc finger and BTB domain containing 48; zinc finger and BTB domain containing 48; telomere zinc finger-associated protein; GLI-Kruppel family member HKR3; krueppel-related zinc finger protein 3; telomeric zinc finger-associated protein; zinc finger and BTB domain-containing protein 48; zinc finger protein 855; 锌指蛋白855; 背景信息: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger and BTB domain-containing protein 48 (ZBTB48), also known as Kruppel-related zinc finger protein 3 or HKR3, is a 688 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZBTB48 is expressed in the adrenal gland and neuroblastoma cell lines. ZBTB48 contains a BTB domain, also known as a POZ domain, which inhibits DNA binding and mediates homotypic and heterotypic dimerization. Characteristics of the BTB domain suggest that ZBTB48 functions as a transcription regulator. 标签:His-tag |
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