蛋白质/抗原/多肽 >> 重组蛋白
重组γ氨基丁酸运载蛋白2
产品介绍 基因名: SLC6A13 产品别名: GAT-2; GAT2; GAT3; SLC6A13; solute carrier family 6 member 13; solute carrier family 6 member 13; sodium- and chloride-dependent GABA transporter 2; GABA transport protein; GABA transporter 2; solute carrier family 6 (neurotransmitter transporter), member 13; solute carrier family 6 (neurotransmitter transporter, GABA), member 13; γ氨基丁酸运载蛋白2; 背景信息: GABA is a major inhibitory neurotransmitter and the GABAergic transmission is terminated by the rapid Na+/Cl-dependent uptake of through GABA transporters. There are multiple subtypes of GABA transporters (GAT1, GAT2, GAT3; and betaine GABA transporter (BGT-1). There is 50% homology between each subtypes. GAT1 and GAT3 have been detected in various parts of the brain while GAT2 is found in many tissues. It appears that GAT1 and GAT3 are involved in distinct GABAergic transmission while GAT2 may be important in non-neural functions. GAT2 is a gamma-amino butyric acid (GABA) transporter. It is a 602 amino acid (85kDa) transmembrane protein. 标签:His-tag |
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