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蛋白质/抗原/多肽 >> 重组蛋白
重组剪接体相关蛋白62
重组剪接体相关蛋白62图片
交货期: 1周
索取资料及报价
交货期:1周
产品别名:Recombinant SF3A2
Recombinant splicing factor 3a subunit 2 protein
产品介绍
基因名:

SF3A2


产品别名:

PRP11; PRPF11; SAP62; SF3a66; SF3A2; splicing factor 3a subunit 2; splicing factor 3a subunit 2; splicing factor 3A subunit 2; SAP 62; pre-mRNA splicing factor SF3A, subunit 2; spliceosome associated protein 62; splicing factor 3a, subunit 2, 66kD; splicing factor 3a, subunit 2, 66kDa; 剪接体相关蛋白62;


背景信息:
SAP 62, also known as SF3A2 (Splicing factor 3A subunit 2), PRP11, PRPF11 or SF3a66, is a 464 amino acid protein that contains one matrin-type zinc finger and belongs to the SF3A2 family. Localized to the nucleus, SAP 62 is a subunit of the SF3A splicing factor, a heterotrimeric complex comprised of three subunits that act in tandem to mediate the binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. The SF3A complex is necessary for the conversion of 15S U2 snRNP into the active 17S protein that performs directly in pre-mRNA splicing events. Functioning as the second subunit of the complex, SAP 62 interacts with subunit 1 (SAP 114) via its N-terminus while simultaneously binding to 15S U2 snRNP via its zinc finger domain. In addition to its role in RNA splicing, SAP 62 is thought to act independently as a microtubule-binding protein.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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