产品介绍 基因名： FARP1 产品别名： CDEP； FARP1-IT1； GLCC1； PLEKHC2； PPP1R75； FARP1； FERM, ARH/RhoGEF and pleckstrin domain protein 1； FERM, ARH/RhoGEF and pleckstrin domain protein 1； FERM, ARHGEF and pleckstrin domain-containing protein 1； FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)； FERM, RhoGEF and pleckstrin domain-containing protein 1； PH domain-containing family C member 2； chondrocyte-derived ezrin-like protein； glycolysis-associated lncRNA of colorectal cancer； pleckstrin homology domain-containing family C member 2； protein phosphatase 1, regulatory subunit 75； 软骨细胞Ezrin样蛋白； 背景信息： FARP1 (FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1), also known as PLEKHC2 or CDEP, is a 1,045 amino acid protein that contains one FERM domain, one DH domain and two PH domains. Existing as multiple alternatively spliced isoforms that are expressed in fetal heart, brain and spleen, as well as in adult lung, kidney and testis, FARP1 is thought to function as a Rho-guanine nucleotide exchange factor that may play a role in linking the cell membrane to the cytoskeleton. The gene encoding FARP1 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome. Trisomy 13, also known as Patau syndrome, is deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections. 标签：His-tag |
相关产品
|
 |
