产品介绍 基因名： BMAL2 产品别名： ARNTL2； CLIF； MOP9； PASD9； bHLHe6； BMAL2； basic helix-loop-helix ARNT like 2； basic helix-loop-helix ARNT like 2； aryl hydrocarbon receptor nuclear translocator-like protein 2； CYCLE-like factor； PAS domain-containing protein 9； aryl hydrocarbon receptor nuclear translocator like 2； basic-helix-loop-helix-PAS protein MOP9； brain and muscle ARNT-like 2； class E basic helix-loop-helix protein 6； member of PAS protein 9； member of PAS superfamily 9； transcription factor BMAL2； 芳香烃受体核转录蛋白样2； 背景信息： BMAL2 is a 636 amino acid protein that localizes to the nucleus and contains one bHLH (basic helix-loop-helix) domain, one PAC (PAS-associated C-terminal) domain and two PAS (PER-ARNT-SIM) domains. Expressed at high levels in placenta and brain and at lower levels in liver, thymus, heart, lung and kidney, BMAL2 functions as a component of the circadian core oscillator, which includes a variety of proteins that work in tandem to activate the transcription of target genes. More specifically, BMAL2, when functioning as a component of the core oscillator, binds to the E-box element (3'-CACGTG-5') of target DNA, thus inducing transcription. Multiple isoforms of BMAL2 exist due to alternative splicing events. 标签：His-tag |
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