蛋白质/抗原/多肽 >> 重组蛋白
重组跨膜蛋白16C
产品介绍 基因名: ANO3 产品别名: C11orf25; DYT23; DYT24; GENX-3947; TMEM16C; ANO3; anoctamin 3; anoctamin 3; anoctamin-3; dystonia 23; transmembrane protein 16C (eight membrane-spanning domains); 跨膜蛋白16C; 背景信息: TMEM16C is a 981 amino acid multi-pass membrane protein that is encoded by a gene which maps to chromosome 11. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, while Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11. 标签:His-tag |
相关产品
|