蛋白质/抗原/多肽 >> 重组蛋白
重组感觉神经蛋白1
产品介绍 基因名: Lratd1 产品别名: 2310003N02Rik; 4731402F03Rik; AW125753; Fam84a; Nse1; Lratd1; LRAT domain containing 1; LRAT domain containing 1; protein LRATD1; family with sequence similarity 84, member A; protein FAM84A; 感觉神经蛋白1; 背景信息: FAM84A is a 292 amino acid protein that belongs to the FAM84 family of proteins. Predominantly expressed in testis, FAM84A shares 44% amino acid identity with the related protein FAM84B. FAM84A localizes to a subcellular membrane region where there is no contact between neighboring cells and is believed to play a role in cell morphology and motility. More specifically, the expression of FAM84A increases cell motility. Two FAM84A isoforms are expressed due to alternative splicing events. Isoform 2 can be phosphorylated on various serine residues and this phosphorylation is associated with cellular morphology. FAM84A is upregulated in colorectal cancer, lung cancer, pancreatic cancer, cholangiocarcinoma and bladder cancer tissues. Via its ability to increase cell motility, FAM84A may contribute to the invasion and metastasis of cancer cells. 标签:His-tag |
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