先天性眼外肌纤维化相关蛋白FEOM2抗体
产品名称 Anti-PHOX2A Anti-paired like homeobox 2A Antibody 产品介绍
靶标: PHOX2A 产品别名: ARIX; CFEOM2; FEOM2; NCAM2; PMX2A; PHOX2A; paired like homeobox 2A; paired like homeobox 2A; paired mesoderm homeobox protein 2A; ARIX1 homeodomain protein; aristaless homeobox homolog; aristaless homeobox protein homolog; arix homeodomain protein; 先天性眼外肌纤维化相关蛋白FEOM2; 背景信息: paired like homeobox 2a(PHOX2A) Homo sapiens The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles. [provided by RefSeq, Jul 2008], 宿主:Rbt 用户评论 产品评分 目前评分共0人 产品质量
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