Azido-PEG1-CH2COO-Cl (compound 43a) is an alkyl/ether-basedPROTAClinker. Azido-PEG1-CH2COO-Cl can be used in the synthesis ofPROTACBRD4 Degrader-1 (HY-133131)^[1].

PROTAC BRD4 Degrader-1 is an efficacious BRD4 degrader with an IC50 of 41.8 nM against BRD4 BD1. PROTAC BRD4 Degrader-1 can effectively degrade BRD4 protein and suppress c-Myc expression^[1].

163.56

C₄H₆ClN₃O₂

79598-49-5

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.