Cyantraniliprole (also known as HGW-86), an anthranilic diamide analog, is a novel and potent second-generation insecticide which is able to deter insect feeding and reduce disease transmission. Cyantraniliprol is a valuable tool for managing Frankliniella occidentalis (Pergande) and also is as effective as abamectin in deterring potato psyllid feeding and could significantly reduce transmission of Lso and the spread of ZC. Cyantraniliprole is approved for use in the United States, Canada, China, and India. Because of its uncommon mechanism of action as a ryanoid, it has activity against pests such as Diaphorina citri that have developed resistance to other classes insecticides. Cyantraniliprole is highly toxic to bees, which resulted in registration of its use as a pesticide being delayed in the USA.
理化性质和储存条件
| Molecular Weight (MW) | 473.71 |
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| Formula | C19H14BrClN6O2 |
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| CAS No. | 736994-63-1 |
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| Storage | -20℃ for 3 years in powder form |
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| -80℃ for 2 years in solvent |
| Solubility (In vitro) | DMSO: 10 mM in DMSO |
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| Water: <1 mg/mL |
| Ethanol: |
| SMILES Code | O=C(C1=CC(Br)=NN1C2=NC=CC=C2Cl)NC3=C(C(NC)=O)C=C(C#N)C=C3C |
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| Synonyms | HGW-86; HGW86; HGW 86. |
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实验参考方法
| In Vitro | In vitro activity: Cyantraniliprole (also known as HGW-86), an anthranilic diamide analog, is a novel and potent second-generation insecticide which is able to deter insect feeding and reduce disease transmission. Cyantraniliprol is a valuable tool for managing Frankliniella occidentalis (Pergande) and also is as effective as abamectin in deterring potato psyllid feeding and could significantly reduce transmission of Lso and the spread of ZC. Cyantraniliprole is approved for use in the United States, Canada, China, and India. Because of its uncommon mechanism of action as a ryanoid, it has activity against pests such as Diaphorina citri that have developed resistance to other classes insecticides. Cyantraniliprole is highly toxic to bees, which resulted in registration of its use as a pesticide being delayed in the USA.
Kinase Assay:
Cell Assay: |
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| References | Pest Manag Sci. 2013 Sep;69(9):1066-72. |
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