Gisadenafil besylate (UK 369003-26) 是一种特异性的口服活性磷酸二酯酶 5 (PDE5) 抑制剂，IC50 为 3.6 nM，可防止环磷酸鸟苷 (cGMP) 降解。
| Cas No. | 334827-98-4 |
| 别名 | UK 369003-26 |
| 化学名 | 5-(2-ethoxy-5-((4-ethylpiperazin-1-yl)sulfonyl)pyridin-3-yl)-3-ethyl-2-(2-methoxyethyl)-2H-pyrazolo[4,3-d]pyrimidin-7(4H)-one benzenesulfonate |
| Canonical SMILES | O=S(N1CCN(CC)CC1)(C2=CC(C(NC3=C(CC)N(CCOC)N=C34)=NC4=O)=C(N=C2)OCC)=O.OS(=O)(C5=CC=CC=C5)=O |
| 分子式 | C23H33N7O5S.C6H6O3S |
| 分子量 | 677.79 |
| 溶解度 | <6.78mg/ml in Water;<67.78mg/ml in DMSO |
| 储存条件 | Desiccate at RT |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
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