Description: Delgocitinib EtOH (LEO-124249; JTE-052) is a novel, potent and selective JAK inhibitor with anti-nflammatory activities and with IC50s of 2.8, 2.6, 13 and 58 nM for JAK1, JAK2, JAK3 and Tyk2, respectively. JTE-052 reduces skin inflammation and ameliorates chronic dermatitis in Comparison with conventional therapeutic agents. JTE-052 regulates contact hypersensitivity by downmodulating T cell activation and differentiation.

纯度：≥98%

CAS：2064338-33-4