Propargyl-PEG4-Boc 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。
生物活性 | Propargyl-PEG4-Boc is a PEG-basedPROTAClinker that can be used in the synthesis ofPROTACs[1]. |
IC50& Target | |
体外研究 (In Vitro) | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Pure form | -20°C | 3 years | | 4°C | 2 years | In solvent | -80°C | 6 months | | -20°C | 1 month |
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