AF-DX 116 (AF-DX 116) 是一种选择性和竞争性的 M2 毒蕈碱乙酰胆碱受体拮抗剂，对兔外周肺和大鼠心脏的 IC50 值分别为 640 nM 和 386 nM。
| Cas No. | 102394-31-0 |
| 别名 | 11-((2-((二乙氨基)甲基)-1-哌啶基)乙酰基)-5,11-二氢-(6H)-吡啶并[2.3-B][1.4]苯并二氮杂-6-酮,AF-DX 116 |
| 化学名 | (S)-11-(2-(2-((diethylamino)methyl)piperidin-1-yl)acetyl)-5H-benzo[e]pyrido[3,2-b][1,4]diazepin-6(11H)-one |
| Canonical SMILES | O=C(CN1[C@H](CN(CC)CC)CCCC1)N2C3=CC=CC=C3C(NC4=CC=CN=C24)=O |
| 分子式 | C24H31N5O2 |
| 分子量 | 421.54 |
| 溶解度 | <10.54mg/ml in DMSO |
| 储存条件 | Store at RT |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
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