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4-Methylumbelliferyl-N-acetyl-α-D-Neuraminic Acid(sodium salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
4-Methylumbelliferyl-N-acetyl-α-D-Neuraminic Acid(sodium salt)图片
CAS NO:76204-02-9
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议

产品介绍
4-Methylumbelliferyl-N-acetyl-α-D-Neuraminic Acid (sodium salt) 是用于神经氨酸酶活性测定的荧光底物。
Cas No.76204-02-9
别名N-乙酰基-2-O-(4-甲基-2-氧代-2H-1-苯并吡喃-7-基)-ALPHA-神经氨酸一钠盐
Canonical SMILESO=C1C=C(C)C2=CC=C(O[C@]3(C([O-])=O)C[C@H](O)[C@@H](NC(C)=O)[C@@]([C@H](O)[C@H](O)CO)([H])O3)C=C2O1.[Na+]
分子式C21H24NO11•Na
分子量489.4
溶解度DMF: 15 mg/ml,DMSO: 20 mg/ml,Ethanol: 0.25 mg/ml,PBS (pH 7.2): 10 mg/ml
储存条件Store at -20℃, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

4-Methylumbelliferyl-N-acetyl-α-D-neuraminic acid is a fluorogenic substrate of neuraminidases. 4-Methylumbelliferyl-N-acetyl-α-D-neuraminic acid is cleaved by neuraminidases to release the fluorescence moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nm, increasing as pH decreases. 4-Methylumbelliferyl-N-acetyl-α-D-neuraminic acid has been used to quantify neuraminidase activity in mammalian cells and clinical isolates of influenza virus.