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Reversine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Reversine图片
CAS NO:656820-32-5
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
10mM * 1mL in DMSO电议

产品介绍

生物活性

Reversine是一种有效的人A3腺苷受体拮抗剂,Ki为0.66μM,是一种泛光A/B/C激酶抑制剂,IC50分别为12 nM/13 nM/20 nM。也用于干细胞去分化。

靶点信息

Aurora AAurora BAurora Chuman A3 adenosine receptor
12 nM13 nM20 nM0.66 μM(Ki)

化学数据

目录号A13250
作用机制Inhibitor (抑制剂), Antagonist (拮抗剂)
M. Wt393.5
FormulaC21H27N7O
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.656820-32-5
Synonyms0
SMILESC1CCC(CC1)NC2=NC(=NC3=C2NC=N3)NC4=CC=C(C=C4)N5CCOCC5

溶解度

In vitroDMSOWarmed: 4 mg/mL (10.17 mM)
WaterInsoluble
EthanolInsoluble
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM25.41 mL127.06 mL254.13 mL
0.5 mM5.08 mL25.41 mL50.83 mL
1 mM2.54 mL12.71 mL25.41 mL
5 mM0.51 mL2.54 mL5.08 mL

*The above data is based on the productmolecular weight 393.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.