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Dopamine serotonin antagonist-1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Dopamine serotonin antagonist-1图片
CAS NO:1977-07-7
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
10mg电议
50mg电议
100mg电议

产品介绍
Dopamineserotoninantagonist-1是dopamine和serotonin受体拮抗剂,对多巴胺D1,D2,D4和血清素S2A,S2C,S3的Ki值分别为200,2500,420,39,84,40nM。
Cas No.1977-07-7
别名氯氮平杂质,Deschloroclozapine
Canonical SMILESCN1CCN(C2=NC3=CC=CC=C3NC4=CC=CC=C42)CC1
分子式C18H20N4
分子量292.38
溶解度DMSO : ≥ 83.3 mg/mL (284.90 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Dopamine serotonin antagonist-1 is a dual dopamine and serotonin receptor antagonist with Kis of 200, 2500, 420, 39, 84, 40 nM for dopamine D1, D2,D4, and serotonin S2A, S2C, S3, respectively.

[1]. Phillips ST, et al. Binding of 5H-dibenzo[b,e][1,4]diazepine and chiral 5H-dibenzo[a,d]cycloheptene analogues of clozapine to dopamine and serotonin receptors. J Med Chem. 1994 Aug 19;37(17):2686-96.