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S-(+)-Marmesin((+)-Marmesin)
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
S-(+)-Marmesin((+)-Marmesin)图片
CAS NO:13849-08-6
包装与价格：
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍
S-(+)-Marmesin ((+)-Marmesin) 是一种天然香豆素，具有 COX-2/5-LOX 双重抑制活性。
Cas No.13849-08-6
别名异紫花前胡内酯,(+)-Marmesin; (S)-Marmesin
Canonical SMILESO=C1C=CC2=CC3=C(O[C@H](C(C)(O)C)C3)C=C2O1
分子式C14H14O4
分子量246.26
溶解度DMSO : 2 mg/mL (8.12 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

S-(+)-Marmesin is a natural coumarin, exhibiting COX-2/5-LOX dual inhibitory activity.

S-(+)-Marmesin ((+)-marmesin) shows affinity at the recombinant psoralen synthase, with a Km of 1.5 ± 0.5 μM, exceeding the substrate affinities of other enzymes of the CYP71 subfamily involved in plant secondary metabolism[1]. S-(+)-Marmesin ((+)-marmesin) shows COX-2/5-LOX dual inhibitory activity[2].

[1]. Larbat R, et al. Molecular cloning and functional characterization of psoralen synthase, the first committed monooxygenase of furanocoumarin biosynthesis. J Biol Chem. 2007 Jan 5;282(1):542-54. Epub 2006 Oct 26. [2]. Kim JS, et al. Chemical constituents of the root of Dystaenia takeshimana and their anti-inflammatory activity. Arch Pharm Res. 2006 Aug;29(8):617-23.