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TFAP
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
TFAP图片
CAS NO:1011244-68-0
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议
100mg电议

产品介绍
TFAP 是一种选择性 cyclooxygenase-1 (COX-1) 抑制剂,IC50 为 0.8 μM。
Cas No.1011244-68-0
别名N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide
Canonical SMILESO=C(NC1=NC=C(N)C=C1)C2=CC=C(C(F)(F)F)C=C2
分子式C13H10F3N3O
分子量281.23
溶解度DMSO : ≥ 155 mg/mL (551.15 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

TFAP is a selective cyclooxygenase-1 (COX-1) inhibitor, with an IC50 of 0.8 uM.

TFAP is a selective cyclooxygenase-1 (COX-1) inhibitor, with an IC50 of 0.8 uM, while that against COX-2 is over 200 uM.

References:
[1]. Kakuta H, et al. Identification of urine metabolites of TFAP, a cyclooxygenase-1 inhibitor. Bioorg Med Chem Lett. 2010 Mar 15;20(6):1840-3.