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Docosatrienoic Acid(cis-13,16,19-docosatrienoic acid)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Docosatrienoic Acid(cis-13,16,19-docosatrienoic acid)图片
CAS NO:28845-86-5
包装与价格:
包装价格(元)
5mg(149 mM*100μL in Ethanol)电议
10mg(149 mM*200μL in Ethanol)电议

产品介绍
二十二碳三烯酸是一种罕见的 ω-3 脂肪酸;抑制 LTB4 与猪中性粒细胞膜的结合,Ki 为 5 μM.
Cas No.28845-86-5
别名顺13,16,19-二十二碳三烯酸,cis-13,16,19-docosatrienoic acid; (13Z,16Z,19Z)-13,16,19-Docosatrienoic acid
Canonical SMILESCC/C=C\C/C=C\C/C=C\CCCCCCCCCCCC(O)=O
分子式C22H38O2
分子量334.54
溶解度Ethanol : 100 mg/mL, DMSO : 100mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Docosatrienoic acid is a rare ω-3 fatty acid; inhibits LTB4 binding to pig neutrophil membranes with an Ki of 5 μM.

Docosatrienoic acid inhibits LTB4 binding to pig neutrophil membranes with an Ki of 5 μM[1].

Application of docosatrienic acid dose-dependently decreases the peak K+ current amplitide and accelerates the potassium activation and inactivation kinetics at all rat membrane potentials[2].

[1]. Yagaloff KA, et al. Essential fatty acids are antagonists of the leukotriene B4 receptor. Prostaglandins Leukot Essent Fatty Acids. 1995 May;52(5):293-7. [2]. Krutetskaia ZI, et al. The effect of docosatrienoic acid on the potassium channels of outward rectification in the membrane of rat peritoneal macrophages. Fiziol Zh Im I M Sechenova. 1995 Jul;81(7):111-9.