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2,4-Diacetylphloroglucinol
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
2,4-Diacetylphloroglucinol图片
CAS NO:2161-86-6
包装与价格：
包装价格(元)
10mg电议
50mg电议
100mg电议

产品介绍
2,4-二乙酰间苯三酚由一些有益细菌荧光假单胞菌的分离物产生，是一种有效的抗生素。
Cas No.2161-86-6
别名2,4-二乙酰基间苯三酚,5-Acetyl-2,4,6-trihydroxyacetophenone,DAPG,1,3-Diacetyl-2,4,6-trihydroxybenzene
化学名1,1'-(2,4,6-trihydroxy-1,3-phenylene)bis-ethanone
Canonical SMILESOC1=C(C(C)=O)C(O)=C(C(C)=O)C(O)=C1
分子式C10H10O5
分子量210.2
溶解度≥ 11.55mg/mL in DMSO
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

2,4-Diacetylphloroglucinol is an agent against various plant pathogenic fungi, viruses, bacteria, and nematodes.

2,4-Diacetylphloroglucinol, a non-nitrogen-containing compound produced by some isolates of P. fluorescens, has been used to increase crop yield by controlling plant root diseases.

In vitro: A previous study was conducted to determine if 2,4-diacetylphloroglucinol was toxic to selected nematodes. The plant-parasitic nematodes including Pratylenchus scribneri and Xiphinema americanum, Heterodera glycines, Meloidogyne incognita, and the bacterial-feeding nematodes such as Pristionchus pacificus, Caenorhabditis elegans, and Rhabditis rainai, were found to be immersed in concentrations ranging from 0 to 100 μg/ml of 2,4-diacetylphloroglucinol. Moreove, the egg hatch and viability of juveniles and adults were determined, and the results showed that 2,4-diacetylphloroglucinol was toxic to X. americanum adults with an LD50 of 8.3 μg/ml. 2,4-Diacetylphloroglucinol could decrease M. incognita egg hatch, but stimulated C. elegans hatch. Whereas, the viability of M. incognita J2 and of C. elegans J1 and adults was not affected. There were no observed effects on the other nematodes. These findings indicated that 2,4-diacetylphloroglucinol was not toxic to all nematodes, and did not affect the tested species of beneficial bacterial-feeding nematodes [1].

In vivo: Up to now, there is no animal in vivo data reported.

Clinical trial: So far, no clinical study has been conducted.

Reference:
[1] Meyer, S. L.F.,Halbrendt, J.M.,Carta, L.K., et al. Toxicity of 2,4-diacetylphloroglucinol (DAPG) to plant-parasitic and bacterial-feeding nematodes. Journal of Nematology 41(4), 274-280 (2009).