| CAS NO: | 564-20-5 |
| 包装 | 价格(元) |
| 5g | 电议 |
| 10g | 电议 |
| Cas No. | 564-20-5 |
| 别名 | 香紫苏内酯 |
| 化学名 | (3aR,5aS,9aS,9bR)-3a,6,6,9a-tetramethyldecahydronaphtho[2,1-b]furan-2(3aH)-one |
| Canonical SMILES | CC(CCC[C@@]1([C@@]2([H])CC(O3)=O)C)([C@]1([H])CC[C@]23C)C |
| 分子式 | C16H26O2 |
| 分子量 | 250.38 |
| 溶解度 | DMF: 30 mg/ml,DMF:PBS (pH 7.2) (1:2): 0.33 mg/ml,DMSO: 15 mg/ml,Ethanol: 10 mg/ml |
| 储存条件 | 4°C, protect from light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Target: NpABC1 IC50: NA Sclareolide (Norambreinolide) is a sesquiterpene lactone natural product derived from various plant sources including Salvia yosgadensis, Salvia sclarea, and cigar tobacco [1]. Sclareolide is a close analog of sclareol, an antifungal diterpene produced at the leaf surface of Nicotiana spp. Moreover, Sclareolide is used as a fragrance in cosmetics and has been more recently marketed as a weight loss supplement. In vitro: Sclareolide (20, 100, and 500 μM) dose-dependently induced NpABC1 expression of a plasma membrane protein in Nicotiana plumbaginifolia cells [1]. Sclareolide (20 μM) had no effect on Nicotiana plumbaginifolia cell growth although the induction of NpABC1 expression. In addition, NpABC1 transcript levels were high 3 hr after sclareolide addition and then decreased. However, the level of NpABC1 protein expression remained fairly stable for up to 12 hr [1]. The 160-kD NpABC1 protein is localized in the plasma membrane and is involved in the secretion of a secondary metabolite which plays an important role in plant defense [1]. In vivo: N/A Reference: |
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