SMO-IN-3

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SMO-IN-3

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

2376914-71-3

包装与价格：

产品介绍

SMO-IN-3 (compound 12a) 是一种有效的smoothened (SMO)抑制剂，对 hedgehog (Hh) 信号通路的IC₅₀为 34.09 nM。SMO-IN-3 对人髓母细胞瘤细胞系 Daoy 有抗增殖作用。具有抗癌活性。

生物活性	SMO-IN-3 (compound 12a) is a potentsmoothened (SMO)inhibitor with anIC₅₀value of 34.09 nM forhedgehog(Hh)signaling pathway. SMO-IN-3 has antiproliferative activity against human medulloblastoma cell line Daoy. Anticancer activity^[1].
IC₅₀& Target	IC₅₀: 34.09 nM (Hh)^[1]
体外研究 (In Vitro)	SMO-IN-3 (compound 12a) has antiproliferative activity against human medulloblastoma cell line Daoy with an IC₅₀of 0.48 μM^[1].
分子量	499.50
Formula	C₂₇H₂₅F₄N₃O₂
CAS 号	2376914-71-3
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.