Bromelain is an anti-inflammatory drug derived from pineapple stem that acts through down-regulation of plasma kininogen, inhibition ofProstaglandin E2expression, degradation of advanced glycation end product receptors and regulation of angiogenic biomarkers as well as antioxidant action upstream in theCOX-pathway^[1]. Bromelain exhibits various fibrinolytic, antiedematous, antithrombotic, and anti-inflammatory activities. Bromelain also possesses some anticancerous activities and promotesapoptoticcell death^[2].

Bromelain (40 mg/kg; intraperitoneal injection; daily; for 7 days; male Sprague-Dawley rats) pretreatment reduces the motor dysfunction in the parkinsonian rat model of parkinson's disease (PD). 6-OHDA injection resulted in marked motor impairment which is prevented by pretreatment with Bromelain prior to the lesion^[1].

Solid

9001-00-7

菠萝蛋白酶；鳳梨酶；菠萝酶；鳳梨酵素

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