Foxy-5 TFA, aWNT5Aagonist, is a mimicking peptide of WNT5A which is a non-canonical member of theWntfamily. Foxy-5 TFA triggers cytosolic free calcium signaling without affectingβ-cateninactivation and it impairs the migration and invasion of epithelialcancercells. Foxy-5 TFA effectively reduces the metastatic spread of WNT5A-low prostatecancercells in an orthotopic mouse model^[1][2][3][4].

WNT5A^[1]

Foxy-5 effectively reduces the metastatic spread of WNT5A-low prostate cancer cells in an orthotopic mouse model^[1].
Foxy-5 reduces the number of colonic cancer stem cells in a xenograft mouse model of human colonic cancer^[2].

808.80

Solid

C₂₈H₄₃F₃N₆O₁₄S₂

MDGCEL

Room temperature in continental US; may vary elsewhere.

Sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

H₂O : 20 mg/mL(24.73 mM;Need ultrasonic)

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80℃, 6 months; -20℃, 1 month (sealed storage, away from moisture)。-80℃ 储存时，请在 6 个月内使用，-20℃ 储存时，请在 1 个月内使用。

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照In Vitro方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用； 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

• 1.

  请依序添加每种溶剂： PBS

  Solubility: 7.14 mg/mL (8.83 mM); Clear solution; Need ultrasonic