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Garetosmab
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:2097125-54-5
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品名称
REGN 2477
产品介绍
Garetosmab (REGN 2477) 是一种全人 IgG4 单克隆抗体,可特异性抑制激活素 A (activin A)。Garetosmab 可用于进行性骨化性纤维发育不良 (FOP) 的研究。
生物活性

Garetosmab (REGN 2477) is a fully humanIgG4monoclonal antibody that specifically inhibitsactivin A. Garetosmab can be used for fibrodysplasia ossificans progressiva (FOP) research[1].

体外研究
(In Vitro)

Garetosmab (REGN 2477) specifically binds to and blocks signaling of activin proteins containing the inhibin βα subunit (activins A, AB, and AC). In vitro, Garetosmab has high affinity and specificity for activins A, AB, and AC, but does not bind or functionally inhibit other TGF-β family ligands that share the same activin receptor pathways, including activin B, inhibin A, BMP-2, BMP6, BMP9, BMP10, GDF8, and GDF11[1].

CAS 号

2097125-54-5

中文名称

加托索单抗

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.