| CAS NO: | 162290-78-0 |
| 包装 | 价格(元) |
| 100mg | 电议 |
| 250mg | 电议 |
| 500mg | 电议 |
| 生物活性 | KRFK, a peptide derived from TSP-1, can activateTGF-β. KRFK promotes TGF-β-mediated signaling and its downstream role, independent of thrombospondin (TSP) receptors such as CD47 and CD36. KRFK can be used for chronic ocular surface inflammatory disorders reseach[1]. |
| IC50& Target | TGF-β[1] |
| 体外研究 (In Vitro) | KRFK (50 μm; 24 h) 激活 TGF-β 的分泌，降低 TSP-1 缺陷骨髓源性树突状细胞 (BMDCs) 中 DC 成熟标记物的表达[1]。 |
| 体内研究 (In Vivo) | KRFK (单只眼用药 5 μg/5 μL; 单剂量) 显著预防 TSP-1-/-小鼠慢性眼表炎症的发生[1]。 |
| 分子量 | 577.72 |
| Formula | C27H47N9O5 |
| CAS 号 | 162290-78-0 |
| Sequence Shortening | KRFK |
| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
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