Lumisterol 3 (>90%) (9β,10α-Cholesta-5,7-dien-3β-ol) is a normal human secosterooid metabolite from the class of vitamin D3 photoisomer derivatives. Lumisterol 3 (>90%) is used in the preparation of vitamin D^[1].

Lumisterol 3 (L3) (1-100 nM, 24 h) significantly reduces UVB-induced cellular oxidant formation in a dose-dependent manner and inhibits the proliferation of UVB-irradiated keratinocytes^[2].
Lumisterol 3 (L3) (100 nM, 24 h) promotes repair of cellular DNA damage induced by UVB irradiation and increases the nuclear/cytosolic Nrf2 ratio and nuclear p53 expression level in UVB-irradiated cells^[2].
Lumisterol 3 (L3) (100 nM, 3 h) significantly enhances the expression levels of Nrf2-regulated antioxidant proteins, including catalase and HO-1 in UVB-irradiated cells^[2].

384.64

Solid

C₂₇H₄₄O

5226-01-7

维生素EP杂质C (lumisterol 3), 光甾醇3

Room temperature in continental US; may vary elsewhere.

-80°C, protect from light, stored under nitrogen

*该产品在溶液状态不稳定，建议您现用现配，即刻使用。

DMSO : 2 mg/mL(5.20 mM;ultrasonic and warming and heat to 60℃)

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