Cyclo(δ-Ala-L-Val) is a bacterial cyclic dipeptide characterized as a diketopiperazine.
| Cas No. | 25516-00-1 |
| Canonical SMILES | O=C(C(N1)=C)N[C@@H](C(C)C)C1=O |
| 分子式 | C8H12N2O2 |
| 分子量 | 168.2 |
| 溶解度 | DMF: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Cyclo(δ-Ala-L-Val) is a bacterial cyclic dipeptide characterized as a diketopiperazine. It activates a LuxR-based N-acylhomoserine lactone (AHL) E. coli biosensor and blocks activation of the biosensor by the quorum sensing signal molecule N-(β-ketocaproyl)-L-homoserine lactone with an IC50 value of 0.8 mM. Cyclo(δ-Ala-L-Val) (15 μM) reduces S. liquefaciens colony expansion by 21%, indicating inhibition of swarming motility. It also inhibits the interaction of the kinases Ras and Raf-1 in a yeast two-hybrid assay in a concentration-dependent manner. |
m.cnreagent.com