ATF3 inducer 1

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ATF3 inducer 1

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

包装与价格：

包装	价格(元)
100mg	电议
250mg	电议
500mg	电议

产品介绍

ATF3 inducer 1 是一种有效的ATF3诱导剂。ATF3 inducer 1 增加 ATF3 蛋白和 ATF3 mRNA 的表达。ATF3 inducer 在小鼠中显示抗 MetS 活性。

生物活性

ATF3 inducer 1 is a potentATF3inducer. ATF3 inducer 1 increases the ATF3 protein and ATF3 mRNA expression. ATF3 inducer 1 shows anti-MetS activity in mouse^[1].

体外研究
(In Vitro)

ATF3 inducer 1 (compound 16c) (50 μM; 8 days) 增加 3T3-L1 细胞中的 ATF3 蛋白和 ATF3 mRNA 表达^[1]。

Western Blot Analysis^[1]

Cell Line:	3T3-L1 cells
Concentration:	50 μM
Incubation Time:	8 days
Result:	Increased the ATF3 protein and ATF3 mRNA expression, showed no lipid accumalation.

体内研究
(In Vivo)

ATF3 inducer 1 (40 mg/kg; i.p.; three times a week for 10-weeks) 在小鼠体内显示出抗 MetS (管理代谢综合征) 活性^[1]。

Animal Model:	Eight-week-old C57BL/6 male mice^[1]
Dosage:	40 mg/kg
Administration:	I.p.; three times a week for 10-weeks
Result:	Decreased the bodyweight and the size of epididymal white adipose tissue (eWAT) adipocytes was notably diminished.

分子量

230.22

Formula

C₁₂H₁₀N₂O₃

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.